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Biomedical Scaffolds

Mykito Chitosan is the purest Non-Animal chitosan in the world. This chitosan is free from beta-glucans, heavy metals, and other contaminants commonly found in conventional chitosan. The Mykito technology is robust, highly repeatable, and consistently produces consistent results.

Dental Implant Scaffolds

The surface of dental implants can be modified with chitosan to enhance healing and osseointegration [Alnufaiy]. . This modification can be achieved by laser-treating the implant prior to chitosan coating, creating biocomposite scaffolds that promote biomineralization and osteoblast formation.

A close-up view of dental crowns being fitted on teeth with a dental dam and metal clamps in place
3D illustration of a human knee joint showing bones and a transparent outline of the leg against a blue background, highlighting Mykito Chitosan for joint support.

Bone Regeneration

Chitosan scaffolds can be customized to create optimal pore size, and surface to promote healing. Its use as a scaffold to encourage the formation of new extracellular matrix assists with cell proliferation and eventual bone regeneration [Tuzlakoglu,Ressler].

This can be applied to dental implants to assist dental pulp regeneration as well  [Moreira, Levengood].

Cardiac Scaffold

Chitosan can be used to fabricate cardiac extracellular matrix scaffolds for repairing congenital defects [Lv]. These implants integrate effectively with body tissues, and their porous structure supports cell survival and proliferation. Chitosan implants can also enhance recovery by minimizing scarring and promoting blood vessel formation following heart attacks [Wang]. Additionally, heart valves can be coated with chitosan to improve their regenerative potential [Jahnavi].

Angiogram image of the heart showing coronary arteries with red contrast dye, overlaid with a cardiac rhythm tracing at the bottom
A 3D illustration of an RNA strand

Stem cell and gene therapy

Following traumatic events such as heart attacks, chitosan can play a key role in cardiac repair. Chitosan-based scaffolds and nanofibers provide an effective platform for cardiac stem cells—or injected stem cells—to grow and proliferate [Patel]. These stem cells can differentiate into cardiac cells, aiding the repair of damaged heart tissue. Additionally, chitosan scaffolds and nanofibers can stimulate genes involved in cardiac contraction and electrical coupling, supporting proper electrical conduction in the heart [Martins].

Tissue Engineering

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Incorporating chitosan into existing 3D scaffolds—or using purely chitosan-based hydrogels—provides a biocompatible surface that supports both blood and cell interactions [Wang]. Chitosan’s versatility allows it to be molded, 3D-printed, coated, or electrospun into various structures, accommodating different cell types and tissue functions.

A digital wireframe model of a human heart in red, set against a blue background with abstract white network lines
A digital medical illustration shows the human liver highlighted in yellow, within a semi-transparent view of the upper torso and internal organs.

Transplant Applications

Chitosan structures can also influence physiological processes, including those of liver and vascular cells, suggesting potential applications as artificial membranes or even organ scaffolds, such as for the liver. However, these applications require further research to fully assess their feasibility and effectiveness. [Sivanesan].

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