Wound Dressings

Mykito Chitosan is the purest Non-Animal chitosan in the world. This chitosan does not have the betaglucins, heavy metals and other contaminants that are commonly found in chitosan. The Mykito technology is robust, repeatable and produces consistent results.

Surgical sutures and Staples

Surgical site infections from fungi and bacteria present great challenges to effective wound healing. By incorporating Chitosan into surgical sutures and staples, its antimicrobial activities can help combat wound site infection and prevent the formation of biofilms. This also further stimulates collagen deposition and blood vessel regeneration to facilitate the wound healing process [Chen,Prabha].

Lacerations

Chitosan, both alone and in combination with growth factors or other biomolecules, can enhance the natural wound healing process. Its use in dressings hastens the process of wound contraction/closure and epithelialization/regeneration [Dai,Obara].

Burns and Trauma

Chitosan and its derivatives can help burn wounds prevent and treat infections while improving its underlying regenerative process [Dai,Sanchez-Machado]. Its control over the physiological environment of wounds allows it to be an effective adjuvant for burn wounds of various thicknesses. It may also be used to deliver a stable source of growth factors and antimicrobial drugs to further assist the healing.

Biocompatibility

The biocompatibility and biodegradability of Chitosan make it an excellent non–toxic, non-permanent material to assist in the healing of wounds. As it acts to promote tissue regeneration and prevent infections while also being slowly processed by the body organically and safely [Dai,Jayankumar].

Hemostasis

Chitosan-based wound dressings can be of great benefit to control bleeding from wounds, especially for patients taking anticoagulants. This can be applied in both low-risk wounds and uncontrolled hemorrhage in emergency circumstances. Chitosan in dressings can encourage platelet adhesion and help activate the coagulation process to slow or stop bleeding quickly [Stricker-Krongrad,Sanjanwala,Wang].

Antimicrobial Activity

The antimicrobial activities of Chitosan can be utilized in wound dressings, creams, and ointments too. Chitosan alone can act as an effective bactericide to facilitate wound healing and even synergize with other antimicrobials like silver to produce even faster destruction of common pathogens like fungi and bacteria [Matica,Ong]. This combinational use can kill up to >99.99% of common bacteria, like P. aeruginosa and S. aureus.

Absorbent Properties

Chitosan-based dressings are excellent at absorbing water and excess fluid from wounds. By addressing moisture levels, maceration can be avoided to provide a clean and optimized environment to heal effectively [Verma,Elangwe].

Reduced Scarring

The incorporation of Chitosan in dressings can also influence scar tissue formation. Chitosan, both alone and in combination with other biomolecules, can alter local physiological processes and protein production to suppress hypertrophic scar formation [Zhang,Anjum].

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