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Drug Eluting Stents

Mykito Chitosan is the purest Non-Animal chitosan in the world. This chitosan does not have the betaglucins, heavy metals and other contaminants that are commonly found in chitosan. The Mykito technology is robust, repeatable and produces consistent results.

Stents

Chitosan-based stents can also be 3D-printed to perform similarly to traditional metal-based stents [Lauto,Qiu]. Their physical properties can be tailored to meet the demands of stenting. This may include customization to be self-expandable while also having the biocompatibility to enhance local tissue regeneration and reduce the need for re-stenting in the future. This can also utilize its drug-carrying capacity to further augment the environment to assist with healing and inflammation.

Medical illustration of a chitosan-coated catheter inserted through a blood vessel and positioned at the aortic valve of the human heart, with the aortic valve labeled.
Medical scan showing highlighted blood vessels and arteries in red against a light background, illustrating the circulatory system

Anticoagulant

Anticoagulants are a mainstay in treating heart attacks, but Chitosan may achieve similar effects without the same risks. The use of Chitosan implants may be able to utilize its anticoagulant properties to prevent blood clots from further forming while maintaining mechanical integrity [Acosta,Imran].

Antimicrobial

Adequate infection control is crucial for any cardiac procedure to avoid severe and prolonged infections. Implants may benefit from the incorporation of Chitosan, as its natural antimicrobial activity provides additional defence against infections following procedures [Yan].

Digital illustration of a human heart surrounded by abstract virus-like particles, featuring neon lines and a network background
A healthcare worker wearing a surgical cap and mask looks down, surrounded by blue surgical drapes

Tissue engineering

Chitosan can be used to create cardiac extracellular matrix scaffolds to repair congenital defects [Lv]. These implants can integrate well into the body tissue and the porous scaffold structure effectively facilitates cell survival and proliferation. Chitosan implants can also improve recovery by limiting scarring and promoting blood vessel development following heart attacks [Wang]. Valves can also be coated in Chitosan to enhance their regenerative potential [Jahnavi].

Drug delivery

The physical and chemical properties of Chitosan make it an excellent carrier of biomolecules to assist in the repair and regeneration of the heart. Its positive charge and hydrophilicity allow a suitable microenvironment to carry and synergize with biomolecules [Patel].

A digital wireframe model of a human heart in red, set against a blue background with abstract white network lines

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