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Pharmaceutical Coatings

Mykito Chitosan is the world’s purest non-animal chitosan, free from beta-glucans, heavy metals, and other common contaminants. The Mykito technology is robust, highly repeatable, and consistently delivers reliable, high-quality results

Drug Delivery Systems

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Chitosan nanoparticles can efficiently encapsulate and deliver drugs in forms such as microparticles, nanoparticles, and hydrogels. This versatility allows their use in both standard and specialized treatments across multiple body systems. Chitosan can be tailored for sustained, controlled, and site-specific drug release [Garg,Su], making it suitable for targeted delivery to tissues including ocular, oral, nasal, and genitourinary systems.

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Illustration of intestinal villi with visible blood vessels and surrounding mucosal surface

Gastrointestinal/ Oral Drug Delivery

One of the main challenges in drug development is ensuring adequate gastrointestinal absorption, and chitosan can also be used as a coating or binding material for tablets, capsules, and granules to protect drugs from the harsh gastrointestinal environment. Through targeted physical and chemical modifications, chitosan can be tailored to resist degradation by low gastric pH, enzymes, and mucus, ensuring effective delivery to the intended sites [Pathomthongtaweechai].

Mucoadhesive Properties

Chitosan’s physical properties make it an effective delivery vehicle by addressing common mucoadhesive challenges. It can adhere to a range of surfaces, including dry epithelial and moist mucosal tissues, enhancing the sustained release and availability of drugs across different tissues [Garg].  Additionally, chitosan can form films that stabilize drug reservoirs, ensuring efficient and controlled delivery.[Campisi,Senel].

non-animal chitosan wound care bandage on forearm
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Solubility Enhancement

Drugs with low water solubility often face absorption challenges, but chitosan can help address this issue. Incorporating and cross-linking such drugs with chitosan can markedly improve their bioavailability. Sharma,Maleki].

Controlled Release

The drug release profile of chitosan nanocapsules and nanospheres can be precisely tailored by modifying their structures. These systems often exhibit a biphasic release pattern, providing an initial rapid release followed by a stable, sustained release to reduce the need for frequent dosing.  [Heriana].

A close-up view of several round, pink tablets, featuring one tablet with chitosan standing upright among others lying flat.
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Weight-loss Adjuvant

Adding chitosan to the diet as a supplement or adjuvant may support weight reduction by binding to dietary fats and limiting their absorption. Animal studies have demonstrated this effect, and some human studies report modest weight improvements in obese participants compared to placebo. [Bull].

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