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Tissue Engineering

Mykito Chitosan is the purest Non-Animal chitosan in the world. This chitosan does not have the betaglucans, heavy metals and other contaminants that are commonly found in chitosan. The Mykito technology is robust, repeatable and produces

consistent results.

Flexible Engineering

Incorporating chitosan into existing 3D scaffolds—or using entirely chitosan-based hydrogels—creates a biocompatible surface that enhances interactions with blood and cells [Wang]. Chitosan’s versatility allows it to be molded, 3D-printed, coated, or electrospun into diverse structures, supporting various cell types and tissue functions.

A scientist wearing a lab coat, mask, and gloves uses a stylus on a tablet in a laboratory setting with test tubes on the table
A digital medical illustration shows the human liver highlighted in yellow, within a semi-transparent view of the upper torso and internal organs.

Transplant Applications

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Chitosan’s effects also extend to modulating physiological processes in cells such as liver and vascular cells. This suggests potential applications in artificial membranes or even organ scaffolds, like the liver, though further research is needed to validate these possibilities [Sivanesan].

Cardiac Tissue Engineering

Chitosan can be utilized to fabricate cardiac extracellular matrix scaffolds for repairing congenital defects [Lv]. These implants integrate effectively with body tissues, and their porous structure supports cell survival and proliferation. Chitosan implants can also aid recovery by reducing scarring and promoting blood vessel formation after heart attacks  [Wang]. Additionally, heart valves can be coated with chitosan to enhance their regenerative potential. [Jahnavi].

Medical scan showing highlighted blood vessels and arteries in red against a light background, illustrating the circulatory system
Medical illustration of a chitosan-coated catheter inserted through a blood vessel and positioned at the aortic valve of the human heart, with the aortic valve labeled.

Stents

Chitosan-based stents can be 3D-printed to function similarly to traditional metal stents [Lauto,Qiu]. Their physical properties can be tailored to meet specific stenting requirements, including self-expansion and enhanced biocompatibility to promote local tissue regeneration and reduce the need for future re-stenting. Additionally, chitosan’s drug-carrying capacity can be leveraged to support healing and modulate inflammation.

Stem cell and gene therapy

Following traumatic events like heart attacks, chitosan can play a key role in cardiac repair. Chitosan-based scaffolds and nanofibers provide an effective platform for cardiac stem cells—or injected stem cells—to grow and proliferate [Patel]. These stem cells can differentiate into cardiac cells, enabling repair of damaged heart tissue. Additionally, chitosan scaffolds and nanofibers can stimulate genes involved in cardiac contraction and coupling, supporting proper electrical conduction in the heart. [Martins].

A DNA double helix with a glowing orange segment, highlighting a chitosan-integrated central section, set against a dark background.
A digital illustration of a complex protein interacting with a strand of RNA

Biocompatibility

Chitosan’s biocompatibility and biodegradability make it an ideal non-toxic, temporary material for supporting wound healing. It promotes tissue regeneration, helps prevent infections, and is gradually and safely metabolized by the body. [Dai,Jayankumar].

Reduced Toxicity

Because chitosan is biologically inert, it mitigates concerns about toxicity and immunogenicity, making it particularly suitable for application to tissues that are susceptible to inflammatory damage [Cao].

Microscopic image of human skin tissue with hair follicles in cross-section, stained to reveal cellular structures in blue, purple, and red

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